STUDY IN THE POTENTIAL OF CHEMICAL COMPOUNDS OF ROSELLA FLOWER (HIBISCUS SABDARIFFA LINN) EXTRACT AS A PREVENTION OF RELAPSE AFTER ORTHODONTIC TREATMENT

  • Farhany Sefina Kusparmanto University of Prof. Dr. Moestopo (Beragama), Jakarta
  • Evie Lamtiur Pakpahan University of Prof. Dr. Moestopo (Beragama), Jakarta
  • Solva Yuditha University of Prof. Dr. Moestopo (Beragama), Jakarta
  • Lukas Kusparmanto University of Prof. Dr. Moestopo (Beragama), Jakarta
Keywords: Flavonoids, tannins, saponins, phytochemicals, orthodontic

Abstract

In dentistry, we can correct malocclusion and malposition by moving the teeth with orthodontic treatment. After the orthodontic treatment is done there’ll still be a possibility of relapse. Relapse is when the teeth return to their original position before the orthodontic treatment was done. The prevalence of relapse after orthodontic treatment is still quite high. Relapse prevention can be achieved through the use of mechanical devices but, they have some limitations. Natural materials can be used as an alternative as the prevention method that can prevent the relapse from happening. Roselle extract contains chemical compounds that have the potential to prevent relapse after the orthodontic treatment is done. To observe the potential of chemical compounds in roselle flower extract as a relapse prevention method after orthodontic treatment. This research was a laboratory experiment. The research phase began with the extraction of rosella flowers (Hibiscus sabdariffa Linn), then continued with the second stage, namely the phytochemical screening of rosella flowers (Hibiscus sabdariffa Linn) using the color reaction method. The phytochemical tests showed that the roselle flower extract contains chemical compounds such as flavonoids, tannins, and saponins. Conclusion: The roselle flower extract contains chemical compounds such as flavonoids, tannins, and saponins, which have anti-inflammatory and antioxidant properties, making it potentially effective in preventing relapse after orthodontic treatment.

References

Amin, M. N., & Permatasari, N. (2016). The Biologic Aspect of Orthodontic Tooth Movement. Stomatognatic , 3(1), 22–27.

Andriekute, A., Vasiliauskas, A., & Sidlauskas, A. (2017). A survey of protocols and trends in orthodontic retention. Progress in Orthodontics, 18(1). https://doi.org/10.1186/s40510-017-0185-x

Arowoogun, J., Akanni, O. O., Adefisan, A. O., Owumi, S. E., Tijani, A. S., & Adaramoye, O. A. (2021). Rutin ameliorates copper sulfate-induced brain damage via antioxidative and anti-inflammatory activities in rats. Journal of Biochemical and Molecular Toxicology, 35(1), 1–8. https://doi.org/10.1002/jbt.22623

Atun, S. (2014). Metode Isolasi dan Identifikasi Struktural Senyawa Organik Bahan Alam. Jurnal Konservasi Cagar Budaya, 8(2), 53–61. https://doi.org/10.33374/jurnalkonservasicagarbudaya.v8i2.132

Badaring, D. R., Sari, S. P. M., Nurhabiba, S., Wulan, W., & Lembang, S. A. R. (2020). Uji Ekstrak Daun Maja (Aegle marmelos L.) terhadap Pertumbuhan Bakteri Escherichia coli dan Staphylococcus aureus. Indonesian Journal of Fundamental Sciences, 6(1), 16. https://doi.org/10.26858/ijfs.v6i1.13941

Dianastesi, S. (2016). Prevalensi Terjadinya Relaps Setelah Perawatan dengan Alat Ortodontik Cekat. Revista CENIC. Ciencias Biológicas, 152(3), 28. file:///Users/andreataquez/Downloads/guia-plan-de-mejora-institucional.pdf%0Ahttp://salud.tabasco.gob.mx/content/revista%0Ahttp://www.revistaalad.com/pdfs/Guias_ALAD_11_Nov_2013.pdf%0Ahttp://dx.doi.org/10.15446/revfacmed.v66n3.60060.%0Ahttp://www.cenetec.

Edrizal, Busman, & Azmir, M. (2021). Evaluation of Relapse after Active Orthodontic Treatment : Scoping Review. Menara Ilmu, XV(01), 43–54.

Fathurrahman, N. R., & Musfiroh, I. (2018). Artikel Tinjauan: Teknik Analisis Instrumentasi Senyawa Tanin. Farmaka, 4(2), 449–456.

Fitriaturosidah, I., Kusnadi, J., Nurnasari, E., Nurindah, & Hariyono, B. (2022). Parameter Spesifik dan Non Spesifik Seduhan Herbal Celup Kelopak Bunga Rosella (Hibiscus Sabdariffa) dengan Penambahan Daun Pandan Wangi (Pandanus Amaryllifolius) dan Kayu Manis (Cinnamomum Burmanii). IOP Conference Series: Earth and Environmental Science, 974(1). https://doi.org/10.1088/1755-1315/974/1/012118

Franzen, T. J., Monjo, M., Rubert, M., & Vandevska-Radunovic, V. (2014). Expression of bone markers and micro-CT analysis of alveolar bone during orthodontic relapse. Orthodontics and Craniofacial Research, 17(4), 249–258. https://doi.org/10.1111/ocr.12050

Goenharto, S., Rusdiana, E., & Khairyyah, I. N. (2017). https://media.neliti.com/media/publications/224514-comparison-between-removable-and-fixed-o-54fba6b7.pdf. Journal of Vocational Health Studies, 01(02), 82–87. www.e-journal.unair.ac.id/index.php/JVHS

Hikmawanti, N. P. E., Fatmawati, S., Arifin, Z., & . V. (2021). Pengaruh Variasi Metode Ekstraksi Terhadap Perolehan Senyawa Antioksidan Pada Daun Katuk (Sauropus androgynus (L.) Merr). Jurnal Farmasi Udayana, 10(1), 1. https://doi.org/10.24843/jfu.2021.v10.i01.p01

Ibrahim, W., Mutia, R., Nurhayati, N., Nelwida, N., & Berliana, B. (2016). Penggunaan Kulit Nanas Fermentasi dalam Ransum yang Mengandung Gulma Berkhasiat Obat Terhadap Konsumsi Nutrient Ayam Broiler. Jurnal Agripet, 16(2), 76–82. https://doi.org/10.17969/agripet.v16i2.4142

James, S. L., Abate, D., Abate, K. H., Abay, S. M., Abbafati, C., Abbasi, N., Abbastabar, H., Abd-Allah, F., Abdela, J., Abdelalim, A., Abdollahpour, I., Abdulkader, R. S., Abebe, Z., Abera, S. F., Abil, O. Z., Abraha, H. N., Abu-Raddad, L. J., Abu-Rmeileh, N. M. E., Accrombessi, M. M. K., … Murray, C. J. L. (2018). Global, regional, and national incidence, prevalence, and years lived with disability for 354 Diseases and Injuries for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017. The Lancet, 392(10159), 1789–1858. https://doi.org/10.1016/S0140-6736(18)32279-7

Kartal, Y., & Kaya, B. (2019). Fixed orthodontic retainers: A review. Turkish Journal of Orthodontics, 32(2), 110–114. https://doi.org/10.5152/TurkJOrthod.2019.18080

Kong, X., Wu, W., Yang, Y., Wan, H., Li, X., Zhong, M., Zhao, H., Su, X., Jia, S., Ju, D., & Lin, N. (2015). Total saponin from Anemone flaccida Fr. Schmidt abrogates osteoclast differentiation and bone resorption via the inhibition of RANKL-induced NF-κB, JNK and p38 MAPKs activation. Journal of Translational Medicine, 13(1), 1–12. https://doi.org/10.1186/s12967-015-0440-1

Kurniawati, I., Maftuch, & Hariati, A. M. (2016). PENENTUAN PELARUT DAN LAMA EKSTRAKSI TERBAIK PADA TEKNIK MASERASI Gracilaria sp. SERTA PENGARUHNYA TERHADAP KADAR AIR DAN RENDEMEN. Samakia: Jurnal Ilmu Perikanan, 7(2), 72–77. http://www.samakia.aperiki.ac.id/index.php/JSAPI/article/view/106

Lai, C. H., Wu, Y. W., Yeh, S. Der, Lin, Y. H., & Tsai, Y. H. (2014). Effects of 6-hydroxyflavone on osteoblast differentiation in MC3T3-E1 cells. Evidence-Based Complementary and Alternative Medicine, 2014. https://doi.org/10.1155/2014/924560

Littlewood, S. J., Kandasamy, S., & Huang, G. (2017). Retention and relapse in clinical practice. Australian Dental Journal, 62, 51–57. https://doi.org/10.1111/adj.12475

Majeed, S. S., & Ghani, B. A. (2018). Effect of Topical Application of Flavonoids Extract of Hibiscus Sabdariffa on Experimentally Induced Bone Defect. Journal of Baghdad College of Dentistry, 30(1), 33–38. https://doi.org/10.12816/0046309

Martin, T. J. (2014). Bone Biology and Anabolic Therapies for Bone: Current Status and Future Prospects. Journal of Bone Metabolism, 21(1), 8. https://doi.org/10.11005/jbm.2014.21.1.8

Ngginak, J., Apu, M. T., & Sampe, R. (2021). ANALISIS KANDUNGAN SAPONIN PADA EKSTRAK SERATMATANG BUAH LONTAR (Borassus flabellifer Linn). BIOEDUKASI (Jurnal Pendidikan Biologi), 12(2), 221. https://doi.org/10.24127/bioedukasi.v12i2.4451

Oktapiya, T. R., Pratama, N. P., & Purnamaningsih, N. (2022). Analisis fitokimia dan kromatografi lapis tipis ekstrak etanol daun rosella (Hibiscus sabdariffa L.). Sasambo Journal of Pharmacy, 3(2), 105–110. https://doi.org/10.29303/sjp.v3i2.181

Pratiwi, Z. A., Herman, H., & Gama, N. I. (2022). Parameter Spesifik dan Non Spesifik Seduhan Herbal Celup Kelopak Bunga Rosella (Hibiscus Sabdariffa) dengan Penambahan Daun Pandan Wangi (Pandanus Amaryllifolius) dan Kayu Manis (Cinnamomum Burmanii). Proceeding of Mulawarman Pharmaceuticals Conferences, 15, 213–217. https://doi.org/10.25026/mpc.v15i1.646

Ratya Utari, T., & Kurnia Putri, M. (2019). Orthodontic Treatment Needs in Adolescents Aged 13-15 Years Using Orthodontic Treatment Needs Indicators. Https://Media.Neliti.Com/Media/Publications/218708-Relaps-Dan-Pencegahannya-Dalam-Ortodonti.Pdf, 2(2), 49. https://doi.org/10.32793/jida.v2i2.402

Santosa, H., Sari, W., & Handayani, N. A. (2018). Ekstraksi Saponin Dari Daun Waru Berbantu Ultrasonik Suatu Usaha Untuk Mendapatkan Senyawa Penghambat Berkembangnya Sel Kanker. Jurnal Inovasi Teknik Kimia, 3(2). https://doi.org/10.31942/inteka.v3i2.2484

Satria Darwis, R., Endro Wahyudi, H., & Kartika, W. (2018). PENGARUH PERAWATAN ORTODONTI DENGAN BEBERAPA JENIS ALAT ORTODONTI TERHADAP PERUBAHAN pH DAN VOLUME SALIVA. Medika Kartika Jurnal Kedokteran Dan Kesehatan, 1(Volume 1 No 2), 126–133. https://doi.org/10.35990/mk.v1n2.p126-133

Schneider, D. A., Smith, S. M., Campbell, C., Hayami, T., Kapila, S., & Hatch, N. E. (2015). Locally limited inhibition of bone resorption and orthodontic relapse by recombinant osteoprotegerin protein. Orthodontics and Craniofacial Research, 18(S1), 187–195. https://doi.org/10.1111/ocr.12086

Suala, H. N., Wibowo, D., & Setyawardhana, R. H. D. (2021). Kebutuhan Perawatan Ortodonti Berdasarkan Index of Orthodontic Treatment Need Pada Remaja. Dentin, 5(3), 129–133. https://doi.org/10.20527/dentin.v5i3.4348

Sukmana, B. I., Budhy, T. I., & Ardani, I. G. A. W. (2017). The potentiation of Mangifera casturi bark extract on interleukin- 1β and bone morphogenic protein-2 expressions during bone remodeling after tooth extraction. Dental Journal (Majalah Kedokteran Gigi), 50(1), 36. https://doi.org/10.20473/j.djmkg.v50.i1.p36-42

Sulistyarini, I., Sari, D. A., & Wicaksono, T. A. (2019). Skrining Fitokimia Senyawa Metabolit Sekunder Batang Buah Naga (Hylocereus polyrhizus). Jurnal Ilmiah Cendekia Eksakta, 56–62.

Vifta, R. L., & Advistasari, Y. D. (2018). Skrining Fitokimia, Karakterisasi, dan Penentuan Kadar Flavonoid Total Ekstrak dan Fraksi-Fraksi Buah Parijoto (Medinilla speciosa B.). Prosiding Seminar Nasional Unimus, 1, 8–14.

Wang, T. yang, Li, Q., & Bi, K. shun. (2018). Bioactive flavonoids in medicinal plants: Structure, activity and biological fate. Asian Journal of Pharmaceutical Sciences, 13(1), 12–23. https://doi.org/10.1016/j.ajps.2017.08.004

Yunitasari, I., Aminin, A. L. N., & Anam, K. (2015). Aktivitas Inhibisi α-Glukosidase dan Identifikasi Senyawa dalam Fraksi Aktif Bunga Rosella (Hibiscus Sabdariffa L.). Jurnal Kimia Sains Dan Aplikasi, 18(3), 110–115. https://doi.org/10.14710/jksa.18.3.110-115

Published
2024-04-30
How to Cite
Kusparmanto, F. S., Pakpahan, E. L., Yuditha, S., & Kusparmanto, L. (2024). STUDY IN THE POTENTIAL OF CHEMICAL COMPOUNDS OF ROSELLA FLOWER (HIBISCUS SABDARIFFA LINN) EXTRACT AS A PREVENTION OF RELAPSE AFTER ORTHODONTIC TREATMENT. Moestopo International Review on Social, Humanities, and Sciences, 4(1), 78-87. https://doi.org/10.32509/mirshus.v4i1.71
Section
Articles